Autism

The incidence of autism spectrum disorders (ASD) has increased dramatically over recent years. In developed countries the incidence has increased by over 600% in the last twenty years.

Other developmental and behavioural disorders like attention deficit disorders (ADD) or attention deficit hyperactivity disorders (ADHD) have also increased and now affect up to 1 out of every 6 children in the U.S.

The Mercury Connection

Mercury is a potent neurotoxin. Worldwide exposure to mercury has increased significantly through fish, industrial sources, vaccinations (containing thimerosal preservative) and dental amalgam fillings. Scientists have found that autistic children may have been exposed to higher amounts of mercury during pregnancy. Glutathione is able to chelate and eliminate mercury and other heavy metals. Glutathione levels are known to be depleted in autistic children.

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Glutathione treatment offers hope for autism

It is known that glutathione levels are depleted in autism. Intravenous glutathione supplementation has shown promising results but the treatment is expensive and time consuming, requiring twice weekly infusions.

The challenge for doctors has been to develop an effective oral supplement, since glutathione is a fragile molecule that is quickly broken down in the digestive system if taken by mouth. 

Following many years of scientific research, effective oral supplements to increase systemic glutathione levels are now available.  Clinically proven oral supplements MaxGXL®, MaxOne™ and Cellgevity™ provide the cells with the essential precursors that they require to make glutathione. Optimised glutathione levels will help to support healthy brain function, detoxify cells, improve mental clarity and reduce inflammation.

Advanced glutathione supplements - MaxGXL, MaxOne and Cellgevity

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Psoriasis

Psoriasis is a chronic autoimmune disease that mainly affects the skin. Non-contagious red, scaly patches are commonly found over the surfaces of the scalp, around or in the ears, the elbows, knees and back.

The scaly patches, also known as psoriatic plaques, are areas of inflammation and excessive skin production. Skin quickly builds up in the affected area, faster than the body’s ability to shed it. Areas with psoriatic plaques take on a silvery-white appearance.

Psoriasis varies in severity - some patients may only have minor localized patches, while others are affected all over the body. Psoriatic nail dystrophy is common among patients with psoriasis - where the fingernails and toenails are affected. Psoriasis may also result in inflammation of the joints, as may be the case with psoriatic arthritis, which affects approximately 10% to 15% of all psoriasis patients.

Psoriasis and the Immune System

Psoriasis is thought to be an immune-mediated disorder in which the excessive reproduction of skin cells is secondary to factors produced by the immune system. Immune T cells (which normally help protect the body against infection) become active, migrate to the dermis and trigger the release of cytokines (tumour necrosis factor-alpha TNFα, in particular) which cause inflammation and the rapid production of skin cells. 

Inflammation and Disease

Tumor necrosis factor (TNF-α) is a cytokine involved in systemic inflammation. The primary role of TNF is in the regulation of immune cells. 

Dysregulation of TNF production causes inflammation and has been implicated in a variety of human diseases, including Alzheimer's disease, cancer, major depression and inflammatory bowel disease (IBD).

Glutathione is a Potent Anti-Inflammatory

In addition to being the body's most powerful antioxidant, glutathione also has potent anti-inflammatory properties. Glutathione helps to reduce the levels of inflammatory cytokines NFKb, TNF and C Reactive Protein, as explained by Dr Don Colbert

Glutathione is Vital for Skin Health

 

Glutathione plays a vital role in skin health and there is evidence to show that glutathione supplementation may help with psoriasis.

Dr Jimmy Gutman explains in his book, Glutathione: Your Body's Most Powerful Protector that psoriasis patients suffer from abnormal glutathione levels, which leads to an excess of damaging free radicals. Dr Gutman says "The clinical results of raising GSH in this disease are promising and more studies are underway..." 

Cellgevity™ is an advanced nutritional supplement containing a unique natural compound called RiboCeine.

RiboCeine™ is clinically proven to significantly increase systemic intracellular glutathione levels, providing a powerful anti-inflammatory action and helping to regulate the immune system. Cellgevity is ideal for promoting a healthy glutathione network, reducing inflammation and supporting optimal skin health. 




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Diabetes

Diabetes mellitus is a group of metabolic diseases in which a person has high blood sugar, either because the body does not produce enough insulin, or because cells do not respond to the insulin that is produced. Prolonged high blood sugar levels can cause serious complications.

Glutathione is the body's most powerful endogenous antioxidant and levels are known to be depleted in people with diabetes. Supplementation with glutathione precursors has been shown to provide many therapeutic effects in diabetes and also helps to improve insulin sensitivity.

"Dietary supplementation with GSH precursor amino acids can restore GSH synthesis and lower oxidative stress and oxidant damage in the face of persistent hyperglycaemia." ~ Sekhar et al, Diabetes Care 2013

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“Administration of glutathione was found to be advantageous in type 2 diabetics and those with impaired glucose tolerance (iGT). Glutathione improved insulin secretion in patients with iGT. Glutathione also improves insulin sensitivity in patients with type 2 diabetes after acute and chronic administration.”

~ Dr Lester Packer Antioxidants in Diabetes Management
  
Oxidative Stress and Diabetes

Glutathione status is closely tied to the progression and severity of diabetes. People with poorly controlled diabetes often have significant depletion of blood glutathione levels. Many of the complications of diabetes are linked to oxidative damage due to the elevated blood sugar levels.

Complications that may arise as a result include damage to the large and small blood vessels ("peripheral vascular disease"); diabetic retinopathy; kidney disease; nerve damage ("neuropathy"); skin problems; dental problems; and increased risk of infection due to a weakened immune system.

As the body's "master antioxidant", glutathione helps to reduce oxidative stress and its consequences. Research studies have shown that supplementation with glutathione precursors may help to reduce oxidant induced diabetic complications such as those shown below.

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Diabetes Affects the Blood Circulation

In a toxic environment, red blood cells stick together and form "Rouleaux" or stacks. This is a very unhealthy state and increases the risk of many diseases. Rouleaux formation occurs in diabetes and is one of the reasons diabetics develop peripheral vascular disease and diabetic retinopathy. Rouleaux formation is also seen in patients with infections, multiple myeloma, inflammatory diseases and cancer.

When red blood cells stack together, it is often an indication of inflammation in the body. Glutathione has powerful antioxidant and anti-inflammatory effects and also improves the endothelial function of blood vessels. Increasing glutathione levels helps the red blood cells to circulate more freely and transport oxygen more effectively. 

Glutathione Deficiency in Diabetes Increases Infection Risk

Research shows that glutathione deficiency in diabetes increases inflammation and also susceptibility to bacterial infection. (Ref: Tan et al, J. Clin Invest. 2012)

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Glutathione Precursors Provide Benefit in Diabetes Management

Cellgevity™ is a powerful antioxidant and anti-inflammatory supplement, designed to dramatically increase systemic glutathione production in every cell of the body. Cellgevity contains the essential glutathione precursors, along with alpha lipoic acid (ALA), a sulphur containing fatty acid that the body requires to convert sugar into energy. Research has shown that ALA improves insulin sensitivity and reduces the incidence of diabetic complications.

Nutrition and Exercise Are Important Too

Dr Don Colbert, author of Reversing Diabetes, discusses natural ways to beat the disease. In addition to recommending glutathione supplementation with Cellgevity, he stresses the importance of good nutrition and exercise. Dr Colbert also discusses the risks of toxic belly fat and recommends reducing the waist line as a very effective strategy to treat or even prevent diabetes.

Decreasing the Waist Line is Vital for Reducing Diabetes Risk 

"Belly fat is highly toxic. After bubble-wrapping itself around internal organs, it secretes powerful inflammatory chemicals that set the stage for type 2 diabetes, heart disease, cancer, and a host of deadly diseases, as well as more weight gain. That is just one of the reasons your first goal should be to decrease the area holding this toxic fat and keeping you susceptible to disease..."
~ Dr Don Colbert "Reversing Diabetes"

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Asthma

Many scientific studies show that chronic oxidative stress and the depletion of the endogenous antioxidant glutathione play a key role in the development of the chronic obstructive pulmonary disease (COPD) and asthma. High oxidative stress coupled with depleted glutathione levels increase inflammation in the airways and accelerate progression of the disease. Studies show the therapeutic effects of restoring glutathione (GSH) levels in asthma and other lung diseases.

"Researchers are beginning to understand why many conditions become chronic and do not resolve despite diligent medical treatment. The oxidative stress (low glutathione) associated with chronic disease may actually disable the "thermostat" called Nrf2 that turns on enzymes that make glutathione. Thus, in conditions such as severe asthma, Nrf2 "burnout" may prevent glutathione formation, leaving the lungs deficient in the glutathione they need for dilation of bronchioles and for proper immune function."  
~ Dr Tim Guildford (What Every Doctor Needs To Know About Glutathione)

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Natural Glutathione Enhancement

It is known that glutathione levels are depleted in asthma and that enhanced glutathione levels are beneficial for lung health, but in practice it can be difficult to effectively increase systemic glutathione levels, as glutathione (GSH) is a fragile molecule that is quickly broken down in the digestive system if taken by mouth. Glutathione must be synthesised within the cell because it cannot be transported into cells.

The glutathione prodrug RiboCeine™ delivers the essential precursor nutrients (ribose and cysteine) to the cell where they can then be turned into glutathione and energy in the form of ATP. RiboCeine has received extensive scientific validation in published peer-reviewed studies and has been shown to increase intracellular glutathione by over 300%. Advanced nutritional supplement Cellgevity™ contains RiboCeine™ along with a selection of natural antioxidant and anti-inflammatory ingredients, ideal for supporting lung health and a healthy immune system.

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Inflammation

We now know that inflammation plays a central role in the chronic illness that remains our number-one killer: coronary artery disease. In fact, elevated markers of silent inflammation, such as homocysteine, CRP, and Lp(a), have been found to be more predictive of heart disease than such traditional risk factors as elevated cholesterol levels (50 percent of those hospitalized for heart disease have normal cholesterol levels).

Although chronic inflammation can cause a variety of disorders, many of us (and unfortunately this includes many physicians) do not know the warning signs of this kind of inflammation or the best ways to treat it. This knowledge is critical because, if a person has one inflammatory condition, the odds that he or she will develop another condition increase dramatically. Researchers have discovered, for example, that a woman with rheumatoid arthritis has a 100 percent increased risk of experiencing a myocardial infarction. And other recent research has demonstrated that higher CRP levels are also associated with age-related macular degeneration, so the same individual can have more than one condition caused by SI. For all these reasons, slowing down this chronic inflammation syndrome is vital to successful age management, so it is crucial that everyone becomes aware of it, understands its causes, and takes measures to stop it.

But Did You Know… Your Body Has A Built-in Mechanism To Fend Off Inflammation: It’s Known As The Super-Hero Of Antioxidants. It’s Name Is: “GLUTATHIONE.” It's the most important molecule you need to stay healthy and prevent disease.

"It's the secret to prevent aging, cancer, heart disease, dementia and more, and necessary to treat everything from autism to Alzheimer's disease." -Dr. Mark Hyman

The leading cause of cellular inflammation is oxidation or the “rusting” of your body’s cells. Hence our need for “anti-oxidants.” But due to the bombardment of toxins in our now highly toxic world on the body’s cells, lifestyle, poor diet, age and stress factors this essential Master antioxidant known as Glutathione diminishes. This circumstance subsequently reveals a complexity and broad spectrum of symptoms. Glutathione also naturally detoxifies from carcinogens and foreign substances. It improves your immune system, and plays a role in DNA repair, protein synthesis and amino acid transportation. Glutathione is also essential to the nervous system, the gastrointestinal system and the lungs.

All inflammation begins at the cellular level, and inflammation is associated with deficient glutathione levels. Glutathione is a powerful natural anti-inflammatory that acts to decrease inflammation and boost the immune system. In scientific studies, supplementation with Cellgevity has been shown to reduce inflammatory markers such as Nuclear Factor Kappa Beta, Tumour Necrosis Factor alpha (TNFa) and C-Reactive Protein (CRP) and to raise the Liver Glutathione by 300%. A product of 40 years of study by one of the leading medicinal chemists and inventors today, it is touted as one of the most powerful supplements that effectively raises glutathione levels to the highest degree.



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Glutathione is Essential for Fertility

Glutathione is the essential molecule that allows the sperm to bind to the egg at conception! Scientific studies have demonstrated that low glutathione levels may be linked with infertility and pregnancy complications.  
There is growing evidence that oxidative stress is a primary cause of male infertility. Decreased glutathione levels have been shown to be linked with poor sperm quality.

Glutathione is also the essential molecule that allows the sperm to bind to the egg at conception.

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