Many scientific studies show that chronic oxidative stress and the depletion of the endogenous antioxidant glutathione
play a key role in the development of the chronic obstructive pulmonary
disease (COPD) and asthma. High oxidative stress coupled with depleted
glutathione levels increase inflammation in the airways and accelerate
progression of the disease. Studies show the therapeutic effects of
restoring glutathione (GSH) levels in asthma and other lung diseases.
"Researchers
are beginning to understand why many conditions become chronic and do
not resolve despite diligent medical treatment. The
oxidative stress (low glutathione) associated with chronic disease may
actually disable the "thermostat" called Nrf2 that turns on enzymes that
make glutathione. Thus, in conditions such as severe asthma, Nrf2
"burnout" may prevent glutathione formation, leaving the lungs deficient
in the glutathione they need for dilation of bronchioles and for proper
immune function."
~ Dr Tim Guildford (What Every Doctor Needs To Know About Glutathione)
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| Click to view abstract |
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| Click to view abstract |
It is known that glutathione levels are depleted in asthma and that enhanced glutathione levels are beneficial for lung health, but in practice it can be difficult to effectively increase systemic glutathione levels, as glutathione (GSH) is a fragile molecule that is quickly broken down in the digestive system if taken by mouth. Glutathione must be synthesised within the cell because it cannot be transported into cells.
The glutathione prodrug RiboCeine™ delivers the essential precursor nutrients (ribose and cysteine) to the cell where they can then be turned into glutathione and energy in the form of ATP. RiboCeine has received extensive scientific validation in published peer-reviewed studies and has been shown to increase intracellular glutathione by over 300%. Advanced nutritional supplement Cellgevity™ contains RiboCeine™ along with a selection of natural antioxidant and anti-inflammatory ingredients, ideal for supporting lung health and a healthy immune system.
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