Glutathione is the body's most powerful endogenous antioxidant and levels are known to be depleted in people with diabetes. Supplementation with glutathione precursors has been shown to provide many therapeutic effects in diabetes and also helps to improve insulin sensitivity.
"Dietary supplementation with GSH precursor amino acids can restore GSH synthesis and lower oxidative stress and oxidant damage in the face of persistent hyperglycaemia." ~ Sekhar et al, Diabetes Care 2013
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“Administration of glutathione was found to be advantageous in type 2 diabetics and those with impaired glucose tolerance (iGT). Glutathione improved insulin secretion in patients with iGT. Glutathione also improves insulin sensitivity in patients with type 2 diabetes after acute and chronic administration.”
~ Dr Lester Packer Antioxidants in Diabetes Management
Oxidative Stress and Diabetes
Glutathione status is closely tied to the progression and severity of diabetes. People with poorly controlled diabetes often have significant depletion of blood glutathione levels. Many of the complications of diabetes are linked to oxidative damage due to the elevated blood sugar levels.
Complications that may arise as a result include damage to the large and small blood vessels ("peripheral vascular disease"); diabetic retinopathy; kidney disease; nerve damage ("neuropathy"); skin problems; dental problems; and increased risk of infection due to a weakened immune system.
As the body's "master antioxidant", glutathione helps to reduce oxidative stress and its consequences. Research studies have shown that supplementation with glutathione precursors may help to reduce oxidant induced diabetic complications such as those shown below.
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Diabetes Affects the Blood Circulation
In a toxic environment, red blood cells stick together and form "Rouleaux" or
stacks. This is a very unhealthy state and increases the risk of many
diseases. Rouleaux formation occurs in diabetes and is one of the
reasons diabetics develop peripheral vascular disease and diabetic
retinopathy. Rouleaux formation is also seen in patients with
infections, multiple myeloma, inflammatory diseases and cancer.
When red blood cells stack together, it is often an indication of inflammation in the body. Glutathione has powerful antioxidant and anti-inflammatory effects and also improves the endothelial function of blood vessels. Increasing glutathione levels helps the red blood cells to circulate more freely and transport oxygen more effectively.
When red blood cells stack together, it is often an indication of inflammation in the body. Glutathione has powerful antioxidant and anti-inflammatory effects and also improves the endothelial function of blood vessels. Increasing glutathione levels helps the red blood cells to circulate more freely and transport oxygen more effectively.
Glutathione Deficiency in Diabetes Increases Infection Risk
Research shows that glutathione deficiency in diabetes increases inflammation and also susceptibility to bacterial infection. (Ref: Tan et al, J. Clin Invest. 2012)
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Glutathione Precursors Provide Benefit in Diabetes Management
Cellgevity™ is a powerful antioxidant and anti-inflammatory supplement, designed to dramatically increase systemic glutathione production in every cell of the body. Cellgevity contains the essential glutathione precursors, along with alpha lipoic acid (ALA), a sulphur containing fatty acid that the body requires to convert sugar into energy. Research has shown that ALA improves insulin sensitivity and reduces the incidence of diabetic complications.
Nutrition and Exercise Are Important Too
Dr Don Colbert, author of Reversing Diabetes,
discusses natural ways to beat the disease. In addition to recommending
glutathione supplementation with Cellgevity, he stresses the importance
of good nutrition and exercise. Dr Colbert also discusses the risks of toxic belly fat and recommends reducing the waist line as a very effective strategy to treat or even prevent diabetes.
Decreasing the Waist Line is Vital for Reducing Diabetes Risk
"Belly fat is highly toxic. After bubble-wrapping itself around internal organs, it secretes powerful inflammatory chemicals that set the stage for type 2 diabetes, heart disease, cancer, and a host of deadly diseases, as well as more weight gain. That is just one of the reasons your first goal should be to decrease the area holding this toxic fat and keeping you susceptible to disease..."
~ Dr Don Colbert "Reversing Diabetes"
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